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Antioxidant, antimicrobial, toxicity and analgesic properties of ethanol extract of Solena amplexicaulis root Biol. Res.
Kabir,Md Golam; Rahman,Md Monsor; Ahmed,Nazim Uddin; Fakruddin,Md; Islam,Saiful; Mazumdar,Reaz Mohammad.
BACKGROUND: This study was subjected to investigate different pharmacological properties of ethanol extract ofSolena amplexicaulis root. RESULTS: The extract contains flavonoid, alkaloid, saponin and steroid compounds. The extract exhibited excellent antioxidant activity in DPPH radical scavenging activity. The extract also showed potent activity in brine shrimp lethality bioassay. The LC50 value was found to 44.677 µg/ml. The extract showed better anti-bacterial activity against gram-negative bacteria. In antifungal assay, the maximum 79.31% of anti-mycotic activity was observed against Aspergillus ochraceus while minimum 44.2% against Rhizopus oryzae. MIC value ranged between 1500 - 3000 µg/ml. The extract was found moderately toxic with a 24-hr LD50...
Tipo: Journal article Palavras-chave: Solena amplexicaulis; Antioxidant; Antimicrobial; Acute toxicity.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100036
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